solitaire stent mri safety

The size of imaging artifacts was measured with all the stents under standardized conditions and with six stents after their implantation into the coronary arteries of freshly explanted pig hearts. Indications, Safety, and Warnings. Garca-Tornel , Requena M, Rubiera M, et al. It is delivered through a standard 0.021" or 0.027" micro catheter on a 0.016" pushwire. Prospective, multicenter, single-arm study of mechanical thrombectomy using Solitaire Flow Restoration in acute ischemic stroke. MRI Safety Coronary Stents Coronary Stents Date of coronary stent placement and device manufacturer should be documented prior to MRI. Interventional Radiology Solitaire AB Neurovascular Remodeling Deviceis designed for thetreatment of intracranial neurovascular disease. 5.2 (MISE JOUR DE 2022) Administration de la thrombolyse intraveineuse La thrombolyse intraveineuse doit tre offerte tous les patients ayant subi un AVC ischmique invalidant qui sont admissibles l'altplase ou la tnectplase dans les 4,5 heures suivant l'apparition des symptmes ou partir du dernier moment o ils ont t vus en bonne sant (recommandation forte . Patients who are ineligible for IV t-PA or who fail IV t-PA therapy are candidates for treatment. This website is based in the U.S. and is subject to the laws and jurisdictions of the United States. ?\IY6u_lBP#T"42%J`_X MUOd Visi-pro balloon expandable vascular and biliary stent, SUPERA Veritas Self-Expanding Nitinol Stent, Maris Deep Infrapopliteal Self-Expanding Stent, Chromis Deep Infrapopliteal Balloon-Expandable Stent, Tsunami Peripheral Balloon-expandable Stent, Continuous Renal Replacement Therapy (CRRT), Percutaneous Ventricular Restoration Therapy. N. Engl. Based on bench and animal testing results. As recently as 10 years ago, the package inserts of many stents, especially uncovered coronary stents, carried a warning not to scan patients in the first 6 weeks unless absolutely necessary. FPE defined as mTICI2c/3; modified FPE defined as mTICI 2b-3. Maximum 15 min of scanning (per sequence). Do not reprocess or re-sterilize. More information (see more) Am J Roentgenol 1999;173:543-546. This site uses cookies to store information on your computer. For vessel safety, do not perform more than three recovery attempts in the same vessel using Solitaire X Revascularization Devices. For each new Solitaire X Revascularization Device, use a new microcatheter. Stent-retriever thrombectomy after intravenous t-PA vs. t-PA alone in stroke. Neurological Advancing the microcatheter while the device is engaged in clot may lead to embolization of debris. This site is Exclusively Sponsored by BRACCO, Orthopedic Implants, Materials, and Devices, Ocular Implants, Lens Implants, and Devices, Cardiovascular Catheters, Other Catheters, and Accessories, Vascular Access Ports, Infusion Pumps*, Catheters, and Accessories, Cerebrospinal Fluid (CSF) Shunt Valves and Accessories. All current, commercially available coronary stents may be imaged at 1.5T or 3T at any time: Maximum whole-body-averaged specific absorption rate (SAR) of 2-W/kg in Normal Operating Mode. Jadhav AP, Desai SM, Zaidat OO, et al. Click OK to confirm you are a Healthcare Professional. per pulse sequence). Porto I, Selvanayagam J, Ashar V, Neubauer S, Banning AP. Judicious selection of patients is necessary, since the use of this device carries the associated risk of stent thrombosis, vascular complications, and/or bleeding events. Jan 1 2015;372(1):11-20. Date of coronary stent placement and device manufacturer should be documented prior to MRI. For a full version of conditions, please see product Instructions for Use (IFU). Oct 2013;44(10):2802-2807. 2022 The Regents of the University of California | Accessibility | Terms of Use | Privacy Policy, (T32) Biomedical Imaging for Clinician Scientists. Case report: 63 year old female present pulsatile headache, diplopia, III. Brand Name: Solitaire X Version or Model: SFR4-3-20-10 Commercial Distribution Status: In Commercial Distribution Catalog Number: Company Name: Micro Therapeutics, Inc. Primary DI Number: 00763000367619 Issuing Agency: GS1 Commercial Distribution End Date: Device Count: 1 Labeler D-U-N-S Number*: 826110710 * Terms of Use The safety and effectiveness has not been established for the Solitaire X device to reduce disability in patients with the following: More distal occlusions in the anterior circulation. Contact Medtronic | Terms of Use | Privacy Statement | Medtronic Manual Library | Choose Region, (such as 9528, 3875-45, 305U219, ENSP30030W), (such as Revo MRI, SynchroMed, Endeavor, Mosaic, Delta, InterStim), (such as pacemaker, stent, otology implants, drug pump), All conditions for use for all implanted devices, The associated risks for a patient with these devices. 1984;61(3):458-467. doi:10.3171/jns.1984.61.3.0458. It is possible that some of the products on the other site are not approved in your region or country. Medtronic Operational Headquarters 710 Medtronic Parkway Minneapolis, MN 55432-5640 USA, Central/Eastern Europe, Middle East & Africa, Electromagnetic Compatibility Guide for Cardiac Devices, Electromagnetic Compatibility for Cardiac Devices, California Transparency in Supply Chains Act, Information About Proposition 65 for California Customers, Digital Millennium Copyright Act (DMCA) Notification, The distinctive, evenly spaced platinum markers enable, Maintains consistent cell size and structure over varying vessel diameters, Provides multiple planes of contact to integrate with the clot, even double layering in smaller vessels, Meaningful visibility with real-time visualization of the radiopaque markers, Evaluate clot composition through body marker integration into the clot, Visualize the expansion and compression of the stent to help. Methods: From the Safe Implementation of Treatments in Stroke-International Stroke Thrombolysis Register, we included consecutive acute ischemic stroke patients (2015-2021) treated within 4.5. Lancet. #vDq2wXbO/D"Od_n00|IV+iZ7D{?Q`8'D1[1^-_S=8rTWZw5SD@n&M66;,AU5 7b ; a+;VAC=` "340pfgv~y?/SOU8dt)&k,S^_*5DSn}(N YVbwcKxNIL|.h~v%Wv-?.\qd wMF{AgeBU*^x@OqVnET.I|a,vv0gF38lN2J}A. The Solitaire device has become the most-published stent retriever with over 200 publications demonstrating clinically proven, tried-and-true performance. Products Stroke. Trevo NXT ProVue Retriever is the next generation of the Trevo evolution, now optimized for combination technique use with aspiration catheters. 4 0 obj The Solitaire X revascularisation device is designed for use in the flow restoration of patients with ischemic stroke due to large intracranial vessel occlusion. J. Med. A nondetachable balloon is inflated in front of the aneurysm neck during coil deposition and removed at the end of the procedure. This is a condition called restenosis. % Carefully inspect the sterile package and the Solitaire X Revascularization Device prior to use to verify that neither has been damaged during shipment. Or information on our products and solutions? The Solitaire X portfolio is designed to give you greater confidence during interventional stroke procedures with: SolitaireTM X Revascularization Device View the features and simulated use of the SolitaireTM X device Few data are available for comparing the therapeutic effects associated with the two mechanical thrombectomy techniques in acute ischemic stroke with atrial fibrillation. Open-cell stent and use of cone-beam CT enables a safe and effective coil embolization of true ophthalmic artery and anterior choroidal artery aneurysms with preservation of parent vessel: Clinical and angiographic results - PMC The new PMC design is here! Refer to the appropriate intravenous tissue plasminogen activator (IV t-PA) manufacturer labeling for indications, contraindications, warnings, precautions, and instructions for use. Do not treat patients with known stenosis proximal to the thrombus site. Stroke. by Model Number (such as 9528, 3875-45, 305U219, ENSP30030W) by Product Name (such as Revo MRI, SynchroMed, Endeavor, Mosaic, Delta, InterStim) by Device Type (such as pacemaker, stent, otology implants, drug pump) Warning: Do not use magnetic resonance imaging (MRI) on a patient who has an implanted device until you review the following: TR-NV13807A, TR-NV15666A, D00419703A, D00324045A. !mqHfALY48 cexRM_ #6O{'_SAK5sUHGOnX-6Aw !664W@q '#qJi&qI This was the first successful human clinical use of a Solitaire stent for this purpose and the ignition spark for the development of a whole generation of new devices, now called stent . Do not cause delays in this therapy. > High field MR imaging: Magnetic field interactions of aneurysm clips, coronary artery stents and iliac artery stents with a 3.0 Tesla MR system. 1,2 The Solitaire X device has a unique parametric design that has been fundamental to the generations of the Solitaire portfolio. Solitaire X If you continue, you may go to a site run by someone else. The distinctive, evenly-spaced platinum markers let you visualise the optimal working length and stent behavior for real-time procedural feedback, ensuring accurate alignment, optimal revascularisation, and clot capture success.2, The 6x40 length device simplifies placement with proximal ophthalmic alignment, providing complete visualisation and coverage from M2 to ICA.4,6, Our SolitaireTM portfolio is backed by published data with 11+ trials and case studies worldwide, proving it reduces stroke-related disability in patients suffering a large vessel acute ischemic stroke following IV t-PA.9-19. Jun 11 2015;372(24):2296-2306. The Solitaire X device is a revascularization device designed for effective clot retrieval during thrombectomy procedures for acute ischemic stroke patients. Metabolic encephalophaties are by definition those disorder of the central nervous system that are not due primarily to structural abnormalities . NOTE: A patient may have more than one implanted device. Products Patients with known hypersensitivity to nickel-titanium. Sorin Allcarbon, AS Model MTR-29AS, 29 mm pyrolitic carbon Heart Valve Sorin Biomedica Cardio S.p.A. Saluggia, Italy treatment of ischemic stroke among patients with occlusion. Shellock R & D Services, Inc. email: Frank.ShellockREMOVE@MRIsafety.com. As an accredited laboratory (ISO 17025), our tests and simulation standards meet the requirements of notified bodies. Tomasello A. Neurological Usable length that is at least as long as the length of the thrombus. Metallic stents may indeed undergo heating during RF-excitation, but this also does not seem to be a major problem even with overlapping stents or with big aortic stent-grafts, in part because flowing blood serves to diffuse away whatever heat is locally generated. The Solitaire X Revascularization Device is indicated to restore blood flow by removing thrombus from a large intracranial vessel in patients experiencing ischemic stroke within 8 hours of symptom onset. Drug-coated stents have been approved for use by the U.S. Food and Drug Administration (FDA). Subscribe to our newsletter. J. Med. 2020 Jun;51(6):e118]. The idea was that the stent needed time to "settle in" and become incorporated in the vessel wall before risking displacement by magnetic forces. Do not torque the Solitaire X Revascularization Device. (17) Sommer T, et al. You can read our Privacy Policy here. Learn more about navigating our updated article layout. Background The number of elderly patients suffering from ischemic stroke is rising. x]6}WjX|}Y<0<4dHwOgb-KV,R%>??(VjqX\.?6Zg3?yQU;CmS6T(o^vYzC5'!ucXSYk$'Ai]SFoO9m4U4]_5-C.6m5E@eTTy\KyG*=gXN| F1t)O}]}(?Z~_,-wky}7 )}-p}y-[JE'!+"{Q%iRMVqITPh>X~F\H[WDD |! Endovascular therapy with the device should be started within 6 hours of symptom onset. Do not recover (i.e. . Less information (see less), Images courtesy of Dr. Alejandro Tomasello Weitz, Differentiated radial outward force promotes clot and vessel wall contact during retrieval with the optimal amount of radial force.10*, A large real-world patient cohort demonstrated a first pass effect (FPE) rate of 40.5% and a modified FPE (mFPE) rate of 58.9% across patients treated with the Solitaire device.14, A large real-world patient cohort demonstrated the following results with the Solitaire device.15, modified Rankin Scale (mRS) 02 at 90days, Symptomatic intercranial hemorrhage (sICH). Endovascular thrombectomy after large-vessel ischaemic stroke: A meta-analysis of individual patient data from five randomised trials. Stroke. SUMMARY: The balloon remodeling technique was initially designed for the endovascular treatment of anatomically complex aneurysms, specifically wide-neck aneurysms. Healthcare professionals must research the conditions for use and instructions for each implanted device before proceeding with MRI procedures. For indication 3, endovascular therapy with the device should be started within 16 hours of symptom onset. The patient's wallet card specifies the model number. It can be scanned safely under the conditions listed in the Instructions . Carry the Patient Implant Card with you at all times and show it to any medical professional who treats you. If excessive resistance is encountered during the delivery of the Solitaire X Revascularization Device, discontinue the delivery and identify the cause of the resistance. The XIENCE Skypoint, XIENCE Sierra and XIENCE Alpine Stent Systems are coated with an everolimus and polymer coating at the full implant stent length. Patients who are ineligible for intravenous tissue plasminogen activator (IV t-PA) or who fail IV t-PA therapy are candidates for treatment. Recanalization rate per retrieval attempt in mechanical thrombectomy for acute ischemic stroke. In addition to conventional T2- and diffusion-weighted MRI, 3D time-of-ight MRA was performed before and after This study explores the use of Solitaire AB as an off-label vascular stent to treat stenoses in the MCA and BA. stream Reasons for Reperfusion Failures in Stent-Retriever-Based Thrombectomy: Registry Analysis and Proposal of a Classification System We do not review or control the content on non-Medtronic sites, and we are not responsible for any business dealings or transactions you have there. Vascular 4 W/kg (first level controlled operating mode), 15 minutes of scanning (i.e., per pulse sequence), In non-clinical testing, the image artifact caused by the GORE, In non-clinical testing, the image artifact caused by the device extends approximately 5 mm from the GORE, Immediately after placement if conditions are met, 10 mm relative to the size and shape of the vascular device, 60 minutes of continuous RF (a sequence or back to back series/scan without breaks). STRATIS, SWIFT PRIME, ESCAPE, Nasa Registry, THRACE, MR CLEAN, STAR, EXTEND IA, HERMES, SEER, REVASCAT, DEFUSE 3, Note: The Solitaire X Revascularization Device was not evaluated in these studies. Serge Bracard, Xavier Ducrocq, et al. Safety of Intra-Arterial Tirofiban Administration in Ischemic Stroke Patients after Unsuccessful Mechanical Thrombectomy . Clot Retrieval Thrombectomy for Acute Ischemic Stroke, Central/Eastern Europe, Middle East & Africa, Acute Ischemic Stroke Revascularisation Products, Access & Delivery Products for Neurovascular, Unique parametric design for dynamic clot integration, Complete visualisation and coverage from M2 to ICA, Optimised delivery system produces lower delivery force, Maintaining consistent stent cell size and structure, Providing multiple planes of clot integration contact, Length from Distal Tip to Flurorosafe marker: <130cm. Administer IV t-PA as soon as possible for all patients who are indicated to receive the drug. You just clicked a link to go to another website. Since the present method of implantation is under a scleral flap, creating a great deal of friction, this study's findings confirm the safety of the Ex-PRESS with MRI testing.The findings also point to the safety of the device if placed directly under the conjunctiva, the originally proposed method of implantation. We ask that our members register with us so that we can maintain the unbiased and independent nature of our content. Adverse reaction to antiplatelet/ anticoagulation agents or contrast media, Device(s) deformation, collapse, fracture or malfunction, Distal embolization including to a previously uninvolved territory, Neurologic deterioration including stroke progression, stroke in new vascular territory, and death, The risk of complication of radiation exposure (e.g., alopecia, burns ranging in severity from skin reddening to ulcers, cataracts, and delayed neoplasia) increases as the procedure time and the number of procedures increase, User experiences major dissatisfaction with device performance. Less information (see less). All current, commercially available coronary stents may be imaged at 1.5T or 3T at any time: Maximum whole-body-averaged specific absorption rate (SAR) of 2-W/kg in Normal Operating Mode. stenting of symptomatic middle cerebral artery stenosis and perioperative evaluation using high-resolution 3 Tesla MRI (2012 . Magnetic Resonance Imaging (MRI) Safety Information for Devices Labeled as MR Conditional The tables show the Gore devices that are labeled as MR conditional. Categorised under: Update my browser now. Possible complications include, but are not limited to the following: Disclaimer: This page may include information about products that may not be available in your region or country. 2013;6:e58e59) wherein a very short left main coronary stent perched at the ostium was found displaced to an iliac artery after a 1.5T MRI was performed 10 days after placement. A randomized trial of intraarterial treatment for acute ischemic stroke. See our stroke products, from stent retrievers to aspiration systems. Circ Stents (non covered ). Cardiovasc Interv. Includes Solitaire FR, Solitaire 2, Solitaire Platinum, Solitaire X. Goyal M, Menon BK, van Zwam WH, et al. The image artifact extends approximately 2 mm from the device, both inside and outside the device lumen. N. Engl. 2016;387(10029):1723-1731. 2016; 15: 113847. This library contains technical information on whether an MRI scan can be performed and how to perform a scan on patients with Medtronic implantable devices. Patients who are ineligible for intravenous tissue plasminogen activator (IV t-PA) or who fail IV t-PA therapy are candidates for treatment. No device migration or heating was induced. Registration is free and gives you unlimited access to all of the content and features of this website. Campbell BC, Mitchell PJ, Kleinig TJ, et al. Some cookies are strictly necessary to allow this site to function. If you don't know the exact model of the stent you are scanning it is therefore safer to use the lower limit. Registration is free and gives you unlimited access to all of the content and features of Which Medical Device. It is delivered througha standard 0.021" or 0.027" micro catheter on a 0.016" pushwire. Advancement of the Solitaire X Revascularizaton Device against resistance may result in device damage and/or patient injury. A stent-graft is an expandable metal stent covered with fabric that forms its own lumen and is commonly placed in aneurysms. N. Engl. Purpose Stent retrievers apply mechanical force to the intracranial vasculature. Initiate mechanical thrombectomy treatment as soon as possible. Mechanical thrombectomy after intravenous alteplase versus alteplase alone after stroke (THRACE): a randomized controlled trial. Our team is happy to help answer any questions you may have. - (00:00), NV AIS Solitaire X Animation 2022;53(2):e30-e32. The MRI safety information is given on the Patient Implant Card. Stroke. For a GORE VIABAHN Endoprosthesis/GORE VIABAHN Endoprosthesis with Heparin Bioactive Surface placed within a bare nitinol stent, the lesser of the maximum whole-body averaged SAR reported in the bare nitinol stents Instructions for Use, or the maximum whole-body averaged SAR of 2.0 W/kg should be used. The tables show the Gore devices that are labeled as MR conditional. See Table XXI in online Data Supplement 1 Downloaded from httpahajournalsorg by from MNGMT 123 at University of Virginia Endovascular therapy with the device should start within 6-16 hours of time last seen well in patients who are ineligible for intravenous tissue plasminogen activator (IV t-PA) or who fail IV t-PA therapy. Less information (see less). The XIENCE V stent should not migrate in this MRI environment. %PDF-1.3 Zaidat OO, Castonguay AC, Linfante I, et al. Find out more Keep up to date Includes Solitaire FR, Solitaire 2. Safety of magnetic resonance imaging in patients with cardiovascular devices: An American Heart Association scientific statement from the Committee on Diagnostic and Interventional Cardiac Catheterization, Council on Clinical Cardiology, and the Council on Cardiovascular Radiology and Intervention: Endorsed by the American College of Cardiology Foundation, the North American Society for Cardiac Imaging, and the Society for Cardiovascular Magnetic Resonance, MRI safety and devices: an update and expert consensus, Safety of magnetic resonance imaging one to three days after bare metal and drug-eluting stent implantation, Metallic stents: Evaluation of MR imaging, Long-term safety of cardiac magnetic resonance imaging performed in the first few days after bare-metal stent implantation. NV AIS Solitaire X Animation Methods We conducted a retrospective analysis of all patients treated for acute ischemic large vessel occlusion stroke with the Solitaire 2 FR 4 40 device between May . This means that the devices have demonstrated safety in a specified MRI environment with the defined conditions of use listed. Based on bench testing results. AIS Revascularization Products Do not use kinked or damaged components. Solitaire X Revascularization Device does not allow for electrolytic detachment. More information (see more) Use of appropriate anticoagulant and/or antiplatelet therapy per standard of care is recommended for use with this stent system. Home Medtronic Data on File. N. Engl. WhichMedicalDevice is a FREE resource created by clinicians for clinicians. 15 minutes of scanning (i.e. In a multinational cohort of 1,604 patients presenting with LVO in the extended window, patients selected by NCCT had comparable clinical and safety outcomes with patients selected by CTP or MRI . Artifacts extended both inside and outside the device lumen. Keywords. The device is a self-expanding stent designed for bridging the neck of aneurysms that can be fully retrieved when fully deployed. Oral presentation at: International Stroke Conference; February 9, 2022; New Orleans, LA. Stroke; a journal of cerebral circulation. 2017;48(10):2760-2768. The aim of this study was to understand the efficacy and safety of MT in elderly patients, many of whom may have baseline impairment. Download the latest version, at no charge. Per IV t-PA manufacturer labeling, IV t-PA should be administered within 3 hours of stroke symptom onset (IV t-PA use beyond 3 hours is not approved in the United States). Warning: Do not use magnetic resonance imaging (MRI) on a patient who has an implanted device until you review the following: Failure to comply with the conditions for use can cause damage to the implanted devices or serious injury to the patient, including death. They are typically inserted during a procedure called. The information from the scan may help your doctor decide if you need another stent. Goyal M, Demchuk AM, Menon BK, et al. Refer to Instructions for Use at eifu.goremedical.com for a complete description of all applicable indications, warnings, precautions and contraindications for the markets where each product is available. Materials and methods: From January 2011 through January 2016, we retrospectively selected 2979 patients with acute ischemic stroke. 36746380_ Neuroimaging of Acute Ischemic Stroke Multimodal Imaging Approach for Acute Endovascular Therapy - Read online for free. Healthcare Professionals Home The powerful magnetic field of the MRI scanner may damage internal metal devices, such as a heart pacemaker. When to Stop [published correction appears in Stroke. The Neuroform (Boston Scientific Corporation, Natick, MA) stent is a self-expanding nitinol stent designed to assist the endovascular placement of detachable coils in wide-necked intracranial aneurysms ( 1, 2 ). Bench testing may not be representative of actual clinical performance. MRI exams are safe for some devices. Medical Information Search If you consent, analytics cookies will also be used to improve your user experience. MRI Information. We've kept the same highly effective Trevo stent, designed to reduce disability in patients experiencing acute ischemic stroke (AIS) up to 24 hours from time last seen well by removing clots to . Cardiac stents are small, metal mesh tubes that are inserted into narrowed or blocked coronary arteries to improve blood flow to the heart. Berkhemer OA, Fransen PS, Beumer D, et al. Copyright 2023 by Shellock R & D Services, Inc. and Frank G. Shellock, Ph.D. All rights reserved. How about other GU devices like nephrostomy tubes and stents? For indication 3, users should validate their imaging analysis techniques to ensure robust and consistent results for assessing core infarct size. Update my browser now. The study will demonstrate safety and efficacy of the SOLITAIRE Device in subjects requiring mechanical thrombectomy diagnosed with acute ischemic stroke. MRI-induced pull back) the device when encountering excessive resistance. The artifact may extend up to 10 mm from the implant. Operators should take all necessary precautions to limit X-ray radiation doses to patients and themselves by using sufficient shielding, reducing fluoroscopy times, and modifying X-ray technical factors whenever possible. Conclusion The Solitaire stent was initially developed for the endovascular treatment of wide necked intracranial aneurysms but has been demonstrated to be safe and efficacious for intracranial thrombectomy. Patients with angiographic evidence of carotid dissection. Healthcare Professionals GORE VIABIL Biliary Endoprosthesis/GORE VIABIL Short WireBiliary Endoprosthesis, GORE TAG Conformable Thoracic Stent Graft, GORE TAG Thoracic Branch Endoprosthesis, GORE EXCLUDER Conformable AAA Endoprosthesis, GORE EXCLUDER Iliac Branch Endoprosthesis, GORE VIABAHN Endoprosthesis/GORE VIABAHN Endoprosthesis with Heparin Bioactive Surface, GORE VIABAHN VBX Balloon Expandable Endoprosthesis, GORE VIATORR TIPS Endoprosthesis/GORE VIATORR TIPS Endoprosthesis with Controlled Expansion. Indications, contraindications, warnings and instructions for use can be viewed at www.medtronic.com/manuals. SMart Piston Otologic Implant Fluoroplastic/Nitinol Gyrus ACMI (Olympus Medical), www.medical.olympusamerica.com Under these conditions, the central portion of the lumen of the aortic component was visible. Registration gives you full access to all of the features of WhichMedicalDevice. ObjectivesThe stent retriever thrombectomy (SRT) and a direct aspiration first-pass technique (ADAPT) are the two main mechanical thrombectomy (MT) techniques for acute ischemic stroke. This device is supplied STERILE for single use only. Stroke. For best results, use Adobe Reader to view Medtronic manuals. Thrombectomy within 8 hours after symptom onset in ischemic stroke. A comprehensive portfolio for all AIS techniques. Stents are widely used throughout the entire arterial system, ranging from vessels several centimeters across (like the thoracic aorta) down to vessels only a few millimeters in diameter (like coronary and intracranial arteries). The best of both worlds: Combination therapy for ischemic stroke. 2017;48(10):2760-2768. Nearly all metal stents are made of non-ferric materials such as 300-series stainless steel, Nitinol, Elgiloy, or other alloys.